NF-κB inducing kinase (NIK) Novel target for cholangiocarcinoma

Molecular targeted drugs targeting the NIK associated with the differentiation factor from hepatocytes to cholangiocarcinoma

Vaccine Adjuvant for the Elderly

Vaccines supplemented with exosomes containing miR-192 show high preventive effect even in the elderly.

Target Discovery and Drug Evaluation using Cancer Stem Cells (CSCs)

We provide CSCs that can be subcultured for a long period of time, which have been enriched and purified from human cancer cells using our proprietary method. We propose joint research projects using these CSCs.

SYT13 Antisense Oligonucleotide for Gastric Cancer Peritoneal Metastasis

Near-term first-in-human ready optimized drug candidate

Proposal of co-development project for RSV (Respiratory syncytial virus) of host-directed therapy

New therapeutic target with low drug resistant acquisition

PeriCyto: A Companion Diagnostics for Immune Checkpoint Inhibitors

Prediction of the efficacy of cancer immunotherapy using the tumor-targeting activity of T cells in peripheral blood.

Efficient method for the production of liposomes containing hydrophilic substances

Efficient encapsulation of hydrophilic small molecules and medium molecular weight drugs such as nucleic acids and peptides in liposomes

miRNA therapeutics targeting RAS networks

High anti-tumor activity for wide range of RAS mutated cancers by chemically-modified miR-143#12 (Tumor-suppressor miRNA)

Improving the efficiency of exogenous mRNA expression

Overcoming the challenges of mRNA medicine by improving translation efficiency

A whole-animal platform for exploring pancreatic cancer drug and combination therapy thereby

Drosophila models for human PDAC genotype

Antisense Oligonucleotide Therapy for Liver Cancer

-Two independent antisense oligonucleotides (ASOs) targeting GREB1 and Arl4c gene-

Cancer vaccine (gene therapy) using adenoviral vector (Ad-REIC)