Thyroid Hormone Receptor-beta (THRβ) Selective Agonist

A small molecule compound that is superior to existing thyroid hormone (TH) analog compounds and applicable for the treatment of NASH, lipid metabolism disorders, and obesity.

Novel NASH Ex vivo Model using Hepatic Organoids Connected to Bile Ducts (HBTO)

Novel therapeutic target for interstitial cystitis

Therapeutic mechanism that differs from conventional treatment methods with the target identified from genetic analysis of model animals and IC patients

Drug Repositioning for Fibrosis Treatment

Only 1/60 dose of anti-hypertensive alleviates fibrosis

Therapeutic Peptide for Autoimmune Diseases

A small peptide that inhibits interaction between STAP-2 and TCR and exhibits immunosuppressive effects.

A new concept for the treatment of allergic dermatitis by targeting glycan receptors on macrophages

Inhibition of TLR4-dependent allergic inflammatory response by Asialoglycoprotein receptor (Asgr1) glycan ligands

Potent Solubilizer for Low-Solubility Aromatic Compounds and its Use

Solubilizer use for experimental formulation of low-solubility seed/hit compounds to evaluate the in vivo drug potency of such compounds.

Liver organoid model containing human hepatocytes for pharmacokinetic assay

Original method and hepatocyte reproduced hepatobiliary function