Novel Therapeutic Agent for Severe Cutaneous Adverse Reactions (SJS/TEN): FPR1 Inhibitor

Suppression of epidermal cell death through control of necroptosis by chenodeoxycholic acid

Branched Chain Amino Acid Prodrug to Increase Muscle and Reduce Fat

Orally available nanoparticles containing BCAA peptides

Mast Cell Line Capable of Cytokine-Free Proliferation

A High-Performance Evaluation Tool Overcoming the Limitations of conventional cells

Small-Molecule erapeutic Targeting Arthritis-Specific Pathology

Suitable for patients with comorbidities

Rheumatoid Arthritis Therapeutics Targeting the Inflammatory Cytokine Sema4D signaling

A Novel Drug Discovery Approach Targeting a Macrophage-Derived Cytokine and Its Downstream Molecules That Induce Cartilage Destruction

New deuterated flow synthesis system for drug development collaboration

Collaborative research on invasive epithelial cells in the precancerous state in interstitial pneumonia and the development of therapeutic agents

Circadian Clock Modulating Drugs for Sleep Disorders and Diabetes Treatment

Two types of seed small molecule compounds (CRY1-A, CRY2-A) that selectively activate the circadian clock regulators CRY1 and CRY2, respectively.

EPA Derivative for Maintaining IBD Remission

Mucin secretion promotion for enhancement of intestinal epithelial barrier function by EPA metabolites produced by intestinal bacteria.

Antiamoebics, Anti-Cancer Agent, Anti-Obesity Agent

Novel ovalicin analog compounds with MetAP2 inhibitory activity show therapeutic effects on various diseases and their synthesis method.

Thyroid Hormone Receptor-beta (THRβ) Selective Agonist

A small molecule compound that is superior to existing thyroid hormone (TH) analog compounds and applicable for the treatment of NASH, lipid metabolism disorders, and obesity.

Novel NASH Ex vivo Model using Hepatic Organoids Connected to Bile Ducts (HBTO)

Novel therapeutic target for interstitial cystitis

Therapeutic mechanism that differs from conventional treatment methods with the target identified from genetic analysis of model animals and IC patients

Drug Repositioning for Fibrosis Treatment

Only 1/60 dose of anti-hypertensive alleviates fibrosis

A new concept for the treatment of allergic dermatitis by targeting glycan receptors on macrophages

Inhibition of TLR4-dependent allergic inflammatory response by Asialoglycoprotein receptor (Asgr1) glycan ligands

Liver organoid model containing human hepatocytes for pharmacokinetic assay

Original method and hepatocyte reproduced hepatobiliary function