NF-κB inducing kinase (NIK) Novel target for cholangiocarcinoma

Molecular targeted drugs targeting the NIK associated with the differentiation factor from hepatocytes to cholangiocarcinoma

Proposal for license and co-development of devices capable of high-speed 68Ga separation and purification as well as automated drug synthesis

A system that makes it possible to synthesize drugs from cyclotron-irradiated solutions with Ga-68 using a hands-free ion trapping device

Friction spot joining of Al alloy and CFRP

A concentric-shaped joining tool that achieve strong joints with low weight (lightweight, compact equipment)

A new concept for the treatment of allergic dermatitis by targeting glycan receptors on macrophages

Inhibition of TLR4-dependent allergic inflammatory response by Asialoglycoprotein receptor (Asgr1) glycan ligands

Co-development proposal via Becker muscular dystrophy (BMD) Cardiomyopathy model swine

A model of BMD with high reproducible of characteristic symptoms that tend to appear cardiac dysfunction earlier than muscle weakness

Prediction of the Efficacy of Cancer Immunotherapy by Direct Measurement of T-cell Cancer Cytotoxic Activity.

Also useful as a companion diagnostics (CDx) for immune checkpoint inhibitors (ICIs).

IBD treatment by intestinal administration of human iPS cell-derived organoids

A mechanism for promoting intestinal tissue regeneration by direct administration of high-quality intestinal organoids with villi-crypt structure derived from human iPS cells into the intestine.

Ornithine/Arginine Nanoparticles for Suppressing Liver Damage in Hyperammonemia

Agrobacterium with highly efficient gene transfer ability to plant

Mechanisms that inhibit the generation of GABA and ethylene during infection, which reduce transformation efficiency

Anti-CD155 antibody treatment for Th1 type autoimmune diseases

Treatment of immunological diseases by a new mechanism to control the immune Th1/Th2 balance