2023-10-31 11:36 am

Antiamoebics, Anti-Cancer Agent, Anti-Obesity Agent

Novel ovalicin analog compounds with MetAP2 inhibitory activity show therapeutic effects on various diseases and their synthesis method.
2023-05-18 21:44 pm

DDS to Activated Macrophages by Advanced Mannose Sugar Chain-loaded Human Serum Albumin

A system that selectively delivers drugs to macrophages in target tissues, such as tumor microenvironments, by means of advanced mannose sugar chain-loaded human albumin designed for the target tissue.
2023-01-05 20:38 pm

Cancer therapy targeting cellular senescence

Novel therapeutic approach targeting the release mechanism of senescence-associated secretory phenotype (SASP) factors from senescent cells
2022-03-07 17:41 pm

STAP-2 Inhibitory Small Peptide for Cancer Treatment

STAP-2 Inhibitory peptide suppresses tumor growth by inhibiting EGFR-STAP-2 interaction and promoting EGFR degradation.
2022-01-13 11:26 am

NF-κB inducing kinase (NIK) Novel target for cholangiocarcinoma

Molecular targeted drugs targeting the NIK associated with the differentiation factor from hepatocytes to cholangiocarcinoma
2021-11-16 16:14 pm

Proposal for Joint Research & Development of Uterine Sarcoma Therapeutics

We are seeking collaborative partners for the non-clinical and clinical development of uterine sarcoma drugs that are inhibitors of cell cycle-related genes CDK1, CDK2, CHEK1, CHEK2, Aurora Kinase B, PLK1, or TTK (Mps1).
2021-07-14 16:47 pm

PeriCyto: A Companion Diagnostics for Immune Checkpoint Inhibitors

Prediction of the efficacy of cancer immunotherapy using the tumor-targeting activity of T cells in peripheral blood.
2020-10-13 06:03 am

A whole-animal platform for exploring pancreatic cancer drug and combination therapy thereby

Drosophila models for human PDAC genotype
2020-06-26 16:28 pm

Potent Solubilizer for Low-Solubility Aromatic Compounds and its Use

Solubilizer use for experimental formulation of low-solubility seed/hit compounds to evaluate the in vivo drug potency of such compounds.

2019-07-26 07:47 am

Liver organoid model containing human hepatocytes for pharmacokinetic assay

Original method and hepatocyte reproduced hepatobiliary function
2018-08-03 04:41 am

STING Ligand Loaded Nano DDS for Cancer Immunotherapy

Original lipid nano particles(LNPs) with INF stimulator(Cyclic-di-GMP) showed dramatic activity as a cancer adjuvant.
2018-04-07 07:18 am

Hypoxia Activated Prodrugs

One step 2-nitroimidazole active site capping of commercialized compound.
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