Enhancing Radiotherapy via DNA Repair Inhibition with Repositioned Azole Compounds
Small molecules that enhance the microtubule polymerization-promoting activity of anticancer drug taxanes.
Development of fluoride-type phosphate prodrugs bearing fluorophosphoramidate as biocompatible functional groups.
Inhibitor of the integrin αV‒CTGF axis, which is activated in response to increased hepatic sinusoidal pressure.
Focus on immune evasion mechanisms and cancer metabolism
Dichloroacetate nanoparticle accumulates in cancer tissue by EPR effect.
Identify platinum-resistant ovarian cancer patients using EV-miRNA markers in body fluids and treat them with JAK inhibitors.
Novel ovalicin analog compounds with MetAP2 inhibitory activity show therapeutic effects on various diseases and their synthesis method.
Molecular targeted drugs targeting the NIK associated with the differentiation factor from hepatocytes to cholangiocarcinoma
Also useful as a companion diagnostics (CDx) for immune checkpoint inhibitors (ICIs).
Original method and hepatocyte reproduced hepatobiliary function
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