Potent Solubilizer for Low-Solubility Aromatic Compounds and its Use

Solubilizer use for experimental formulation of low-solubility seed/hit compounds to evaluate the in vivo drug potency of such compounds.

Sulfasalazine for Anti-Canine Melanoma

Therapeutic agent for hearing loss

New chemical entities can rescue from hearing loss caused by a chemotherapy drug cisplatin

Liver organoid model containing human hepatocytes for pharmacokinetic assay

Original method and hepatocyte reproduced hepatobiliary function

C16orf74 Blocker for Pancreatic Cancer Therapy

Blocking C16orf74 dimerization suppresses pancreatic cancer growth and invasion.

STING Ligand Loaded Nano DDS for Cancer Immunotherapy

Original lipid nano particles(LNPs) with INF stimulator(Cyclic-di-GMP) showed dramatic activity as a cancer adjuvant.

5-Fluorouracil / Doxorubicin / Gemcitabine based Prodrugs Targeting Hypoxia

Protection of active site by 2-nitroimidazole is released in hypoxia

Promising druggable target for c-Myc

Inhibitor of Runx3 binding site on c-Myc promoter enable innovative anti-cancer therapy.

4th generation EGFR-TKI

Tyrosine kinase inhibitor(TKI) for drug-resistant EGFR mutant