Sugar / Lipid / Peptide / Protein / Antibody / Enzyme

2025-05-16 9:37 pm

Therapeutic Drug for Achondroplasia

The approved antihistamine meclizine promotes cartilage formation by suppressing excessive signaling caused by FGFR3 mutations.

2025-05-16 9:32 pm

Urinary Biomarker for Aging Assessment

L-Saccharopine: A Metabolic Marker Reflecting Mitochondrial Dysfunction as an Indicator of Aging

2025-05-16 9:26 pm

Rett Syndrome Therapeutic Drug

We have recently discovered that an already approved small-molecule therapeutic drug is effective against Rett syndrome. We propose the development of a new drug for Rett syndrome by repositioning the drug.

2025-05-16 9:33 pm

Enhancer of Anticancer Drug Taxanes

Small molecules that enhance the microtubule polymerization-promoting activity of anticancer drug taxanes.

2025-05-16 9:34 pm

Therapeutic and Prophylactic Drugs for Idiopathic Osteonecrosis of the Femoral Head (ONFH)

2025-05-16 9:35 pm

A Method for Elongating Peptide Chains Two Residues at a time

A method for synthesizing two-residue elongated peptides using microflow synthesis, taking advantage of both the nucleophilic and electrophilic reactivity of amino acid N-carboxyanhydrides (NCAs).

2025-05-16 9:11 pm

Synthesis of Peptides Combining α-Disubstituted Amino Acids (Aib) and N-Methyl Amino Acids

A method for synthesizing a peptide composed of bulky Aib and N-methyl amino acids using a microflow synthesis.

2025-05-16 9:02 pm

Enhanced mRNA Expression Platform Using Synthetic 5’UTR Repeat Sequence

Inserting 50-nucleotide synthetic repeat sequences into the 5’UTR significantly enhances mRNA translation, achieving up to 10-fold increases in protein expression in both cells and animals

2025-05-09 1:16 pm

Branched Chain Amino Acid Prodrug to Increase Muscle and Reduce Fat

Orally available nanoparticles containing BCAA peptides

2025-05-09 12:51 pm

Mast Cell Line Capable of Cytokine-Free Proliferation

A High-Performance Evaluation Tool Overcoming the Limitations of conventional cells