Proposal for a project to establish imaging technology for male infertility through the application of MRI technology

Anti-Obesity and/or Anti-Diabetes Drug

Therapeutic mechanism based on enhancement of adipocyte activation (promotion of UCP1 expression and mitochondrial activation) by SerpinA1.

Novel NASH Ex vivo Model using Hepatic Organoids Connected to Bile Ducts (HBTO)

Atrial Fibrillation Risk/Severity Diagnostic Device

Device equipped with an AI program that can diagnose the risk and severity of paroxysmal atrial fibrillation from as little as 30 consecutive beats of ECG data.

Induction of highly purified differentiation of endothelial progenitor cells (EPCs) from iPS cells and BBB model using brain microvascular endothelial-like cells (iBMELCs)

Optimized induction of iBMELCs differentiation from iPS cell-derived vascular endothelial progenitor cells (iEPCs) successfully induced cells with gene expression and barrier function like human BMECs.

Cancer therapy targeting cellular senescence

Novel therapeutic approach targeting the release mechanism of senescence-associated secretory phenotype (SASP) factors from senescent cells

Semi-quantitative determination of equilibrium constants of molecules using particle dissociation by ultrasonic radiation force

Enables measurement of ultra-trace samples and weak intermolecular forces in a short time

Therapeutic Medicine for Infectious Diseases (COVID-19) Targeting the Vascular Barrier

Small Molecule enhances Claudin-5 (CLDN5) function, which organizes tight junctions between vascular endothelial cells. And prevents vascular barrier disruption by pathogens, including COVID-19

Polylactic acid blend polymer with better impact resistance than ABS resin

Twice the impact resistance of ABS resin and more than 30 times the impact resistance of PLA

Low dropout regulator circuit that achieves both high noise rejection performance and extremely low power consumption