For acute kidney injury, inflammatory bowel disease, depressions, etc.
Therapeutic target molecules and antisense oligonucleic acid (ASO) therapeutic agents for autosomal dominant polycystic kidney disease (ADPKD).
Peptide linker enhances the interaction between VH-VL within scFv molecules, which suppresses intermolecular association.
A novel therapeutic approach for systemic anti-tumor immunity utilizing apolipoproteins
Splice-switching antisense oligonucleotides (SSOs) targeting the α-synuclein (SNCA) gene suppress α-synuclein (α-Syn) aggregation.
Discovery of Induction Method from Dental Pulp Cells to Odontoblasts
A new therapeutic concept to prevent cellular infiltration into inflamed tissues by targeting the nets structures (Myl9-nets) generated in the lumen of blood vessels.
New chemical entities promoting degradation of ubiquitinated protein aggregates through induction of selective autophagy
Novel ovalicin analog compounds with MetAP2 inhibitory activity show therapeutic effects on various diseases and their synthesis method.
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