Identification of prostaglandin receptors involved in the pathogenesis of endometriosis. [Collaborative Research Proposal]
Oral DDS technology using cyclic peptides of D-amino acids that can reach the small intestine while suppressing degradation in the digestive tract and allowing highly efficient permeation through the intestinal epithelium.
For acute kidney injury, inflammatory bowel disease, depressions, etc.
Therapeutic target molecules and antisense oligonucleic acid (ASO) therapeutic agents for autosomal dominant polycystic kidney disease (ADPKD).
Peptide linker enhances the interaction between VH-VL within scFv molecules, which suppresses intermolecular association.
A novel therapeutic approach for systemic anti-tumor immunity utilizing apolipoproteins
Splice-switching antisense oligonucleotides (SSOs) targeting the α-synuclein (SNCA) gene suppress α-synuclein (α-Syn) aggregation.
Discovery of Induction Method from Dental Pulp Cells to Odontoblasts
ASO-4733: Optimized Anti-SYT13 antisense oligonucleotides
A new therapeutic concept to prevent cellular infiltration into inflamed tissues by targeting the nets structures (Myl9-nets) generated in the lumen of blood vessels.
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