A novel therapeutic approach for systemic anti-tumor immunity utilizing apolipoproteins
Splice-switching antisense oligonucleotides (SSOs) targeting the α-synuclein (SNCA) gene suppress α-synuclein (α-Syn) aggregation.
Discovery of Induction Method from Dental Pulp Cells to Odontoblasts
A new therapeutic concept to prevent cellular infiltration into inflamed tissues by targeting the nets structures (Myl9-nets) generated in the lumen of blood vessels.
New chemical entities promoting degradation of ubiquitinated protein aggregates through induction of selective autophagy
Novel ovalicin analog compounds with MetAP2 inhibitory activity show therapeutic effects on various diseases and their synthesis method.
Mechanism of inhibition of nuclear translocation of phosphorylated Smad and induction of differentiation into Myofibroblast
Enhance the effectiveness of existing laser treatments by administering carbon monoxide-bound hemoglobin vesicles (CO-HbV), which have been developed as artificial red blood cells.
Targeting soluble CD155, an immune escape mechanism of tumor cells, activates cancer immunity through DNAM-1-mediated activation signals on T cells
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