Nanoparticles Comprising Polylysine Dendrimer Derivatives, Anionic Polymers, and Nucleic Acids
Collaborative research proposals using this discovery platform.
D35LNPs stimulate TLR9 and significantly induce the release of IFN-α from plasmacytoid dendritic cells, thereby strongly enhancing systemic immunity
Polymeric nanoparticles with high specificity compared to an existing drug
Dichloroacetate nanoparticle accumulates in cancer tissue by EPR effect.
Proposed collaboration to develop ARVC therapies (e.g., gene therapy or mRNA therapy) using PKP2 mutant disease model cells from ARVC patients and corresponding recovery cells.
Inhibition of TLR4-dependent allergic inflammatory response by Asialoglycoprotein receptor (Asgr1) glycan ligands
Overcoming the challenges of mRNA medicine by improving translation efficiency
Original method and hepatocyte reproduced hepatobiliary function
Useful for gene therapy by minimizing non-homologous end joining (NHEJ) derived Insertions or deletions (Indels)
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