Donor DNA-free, DSB-free Precise CRISPR Gene Editing

Disease modifying somatic cell correction with minimized risk of on/off target derived indels or random integration of donor DNA.

Orally available formulation of Short-Chain-Fatty-Acid (SCFA)

Phage therapy for Vancomycin-resistant Enterococcus (VRE)

We identified several bacteriolytic phage strains against Enterococcus species widely including VRE and confirmed therapeutic effect in endophthalmitis model.

Liver organoid model containing human hepatocytes for pharmacokinetic assay

Original method and hepatocyte reproduced hepatobiliary function

Neuroprotectant for Acute Ischemic Stroke

Micellized Free Radical Scavenger Prodrug

Virus agent for treatment of Fibrosis

Repositioning reovirus, which has been developed as an anti-cancer drug.

Precise, Efficient Somatic Cell CRISPR HDR Gene Correction

Useful for gene therapy by minimizing non-homologous end joining (NHEJ) derived Insertions or deletions (Indels)

Cancer vaccine (gene therapy) using adenoviral vector (Ad-REIC)