A new concept in therapeutics targeting molecules associated with vascular inflammation
Novel targets identified from genetic analysis of a model animal and patients that differ from previous therapeutic approaches
Novel target molecules of the ergosterol synthesis pathway, a critical gene for Candida
Cell membrane-derived vesicles of target bacteria can be used to develop activation products for specific enteric bacteria and antibacterial agents against biofilm-producing bacteria
Safe molecular design that allows RI to be rapidly excreted into the urine by providing a tubule-specific enzyme cleavage sequence between the RI chelating site and the antibody
Identification of prostaglandin receptors involved in the pathogenesis of endometriosis. [Collaborative Research Proposal]
Oral DDS technology using cyclic peptides of D-amino acids that can reach the small intestine while suppressing degradation in the digestive tract and allowing highly efficient permeation through the intestinal epithelium.
For acute kidney injury, inflammatory bowel disease, depressions, etc.
Therapeutic target molecules and antisense oligonucleic acid (ASO) therapeutic agents for autosomal dominant polycystic kidney disease (ADPKD).
Peptide linker enhances the interaction between VH-VL within scFv molecules, which suppresses intermolecular association.
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