Synthesis of Peptides Combining α-Disubstituted Amino Acids (Aib) and N-Methyl Amino Acids

A method for synthesizing a peptide composed of bulky Aib and N-methyl amino acids using a microflow synthesis.

Branched Chain Amino Acid Prodrug to Increase Muscle and Reduce Fat

Orally available nanoparticles containing BCAA peptides

Development of Phosphate Prodrug Compounds of Nucleic Acid Analogues

Development of fluoride-type phosphate prodrugs bearing fluorophosphoramidate as biocompatible functional groups.

A Novel Therapeutic Drug for Niemann-Pick Disease Type C

Ceramide Kinase Inhibitor that Improves Intracellular Lipid Transport Disorders

DDS Carrier Composed of Biodegradable Materials with High Gene Expression Efficiency

Nanoparticles Comprising Polylysine Dendrimer Derivatives, Anionic Polymers, and Nucleic Acids

Biofilm-Controlled Drug: Sensitivity Enhancer

Enhancing Antibiotic Efficacy by Regulating Electron Transfer with Redox Molecules

Rheumatoid Arthritis Therapeutics Targeting the Inflammatory Cytokine Sema4D signaling

A Novel Drug Discovery Approach Targeting a Macrophage-Derived Cytokine and Its Downstream Molecules That Induce Cartilage Destruction

Small molecule compounds that facilitate drug delivery to the brain

Blood-Brain Barrier DDS Peptide

A cyclic peptide for highly efficient delivery into the brain with macromolecular drugs.

Treatment and Biomarker for Hepatocellular Carcinoma caused by Sinusoidal Hypertension

Inhibitor of the integrin αV‒CTGF axis, which is activated in response to increased hepatic sinusoidal pressure.