Inhibitor of the integrin αV‒CTGF axis, which is activated in response to increased hepatic sinusoidal pressure.
Small-Molecule Compounds Promoting Selective Autophagy (Xenophagy) for Bacterial Elimination
Placing a sheath over the stenosis in the bile duct drainage prevents restenosis after removal of the balloon catheter and simplifies stent insertion
Discovery of a new mechanism of hypertension induction and proposal for drug discovery collaboration based on the mechanism.
New therapeutic targets and therapeutic agents for trauma-induced heterotopic ossification in FOP patients.
This technology utilizes small-molecule ligands that enhance the efficacy of oligonucleotide therapeutics in reducing gene expression within the spleen.
D35LNPs stimulate TLR9 and significantly induce the release of IFN-α from plasmacytoid dendritic cells, thereby strongly enhancing systemic immunity
An approach to enhance mechanical stress responsiveness via activation of Piezo1 shows promise in improving bone mass and strength in patients with glucocorticoid-induced osteoporosis (GIOP).
siRNAs containing innovative artificial nucleic acids selectively suppress mRNAs containing abnormally expanded CAG repeats
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