Introducing rhodopsin mutants into host organisms significantly enhances bioprocess productivity through light-driven ATP regenerating
siRNAs containing innovative artificial nucleic acids selectively suppress mRNAs containing abnormally expanded CAG repeats
Predicting therapeutic efficacy of combined immunotherapy such as atezolizumab/bevacizumab using CD14+ monocyte/CD4+ T cell subsets as an indicator
Specific gene transfer only to the site of placentation without affecting the fetus.
RNA-binding molecules, such as antisense oligonucleotides and small molecules, facilitate back-splicing progression and augment circular RNA
Compaction of long-chain plasmid DNA of 10 kbp or more achieves highly efficient intracellular uptake and protein expression.
Selection of oocytes using follicular fluid miRNA markers that correlate with pregnancy outcome can provide fertility treatments with high pregnancy rates
A novel analyzing method for DNA molecules of size greater than 10 kbp by measuring DNA relaxation time with micro/nanofluidic devices
Useful for gene therapy by minimizing non-homologous end joining (NHEJ) derived Insertions or deletions (Indels)
Achieved targeted large size gene knock-in animal production.
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