{"id":4651,"date":"2025-07-14T11:09:05","date_gmt":"2025-07-14T02:09:05","guid":{"rendered":"https:\/\/bionauts.jp\/?p=4651"},"modified":"2025-07-15T15:49:52","modified_gmt":"2025-07-15T06:49:52","slug":"key-factors-in-electronic-materials-deuterated-materials-production","status":"publish","type":"post","link":"https:\/\/bionauts.jp\/?p=4651","title":{"rendered":"Key factors in electronic materials, deuterated materials production"},"content":{"rendered":"<h3>Advantages<\/h3>\n<ul>\n<li><strong>Low environmental impact reactions; no high pressure, low temperature reactions (about 25 \u00b0C) and no deuterium gas<\/strong><\/li>\n<li><strong>High reaction performance<\/strong><strong>\uff08<\/strong><strong>80-99<\/strong><strong>\uff05<\/strong><strong> introduction, 80-98<\/strong><strong>\uff05<\/strong><strong> yield<\/strong><strong>\uff09<\/strong><\/li>\n<li><strong>Can be used for a wide range of compounds, post-synthesis and on-demand synthesis<\/strong><\/li>\n<li><strong>Raw material, deuterated water (D<sub>2<\/sub>O) is reusable and easily purified from the catalyst<\/strong><br \/>\n<h3>Background &amp; Technology<\/h3>\n<p>Recently, properties that improve chemical stability and thermal properties have been found in the performance of electronic materials through deuteration. Deuteration is also attracting attention as a way to improve the properties, longevity, and power savings of light-emitting materials used in OLED panels by reducing the expansion and contraction frequency and increasing the efficiency of thermal energy, and is becoming a trend in materials development. On the other hand, all conventional deuteration processes are batch-type deuteration methods using organic synthesis processes, and the complexity and cost of treatment methods and processes have been an issue.<br \/>\nThe laboratory has developed a deuterium-labelled compound flow synthesis system that can be processed at ambient pressure and room temperature, using a process that does not involve organic synthesis and does not produce a large amount of waste and demonstrated deuterated pharmaceutical.<br \/>\nTo be specific, the device concept is to supply heavy water (D2O) and a proton source to the anode side of the proton-conducting membrane and a compound to be deuterated to the cathode side of the proton-conducting membrane by means of a new membrane-type reactor with electrodes attached to the proton-conducting membrane. Nafion and graphene oxide membranes are currently used as proton-electric membranes. Deuterium-labelled compounds are electrochemically synthesized by energizing a proton-conducting membrane, whereby the proton source and heavy water are electrochemically oxidized as H+\/D+ on the anode side and react with the deuterated compound as D+\/D2 that passes to the cathode side via the proton-conducting membrane.<br \/>\nThis system will contribute to the R&amp;D\/manufacturing stages of a wide range of materials, and by enabling mass production, it is likely to revolutionize the process by enabling the rapid provision of high-performance electronic materials development.<\/li>\n<\/ul>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 100%;\"><a href=\"http:\/\/bionauts.jp\/wp-content\/uploads\/2025\/07\/ON-04951b.png\"><img decoding=\"async\" loading=\"lazy\" class=\"alignleft size-large wp-image-4652\" src=\"http:\/\/bionauts.jp\/wp-content\/uploads\/2025\/07\/ON-04951b-1024x432.png\" alt=\"\" width=\"840\" height=\"354\" srcset=\"https:\/\/bionauts.jp\/wp-content\/uploads\/2025\/07\/ON-04951b-1024x432.png 1024w, https:\/\/bionauts.jp\/wp-content\/uploads\/2025\/07\/ON-04951b-300x126.png 300w, https:\/\/bionauts.jp\/wp-content\/uploads\/2025\/07\/ON-04951b-768x324.png 768w, https:\/\/bionauts.jp\/wp-content\/uploads\/2025\/07\/ON-04951b-1536x648.png 1536w, https:\/\/bionauts.jp\/wp-content\/uploads\/2025\/07\/ON-04951b-2048x863.png 2048w, https:\/\/bionauts.jp\/wp-content\/uploads\/2025\/07\/ON-04951b-1200x506.png 1200w\" sizes=\"(max-width: 709px) 85vw, (max-width: 909px) 67vw, (max-width: 1362px) 62vw, 840px\" \/><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Researcher<\/h3>\n<p>Kumamoto University \u00a0Department of Applied Chemistry and Biochemistry\u00a0 Professor Testuya Kida<\/p>\n<h2>Patent<\/h2>\n<p>Pending\uff08International phase, unpublished\uff09<\/p>\n<h3>Publication<\/h3>\n<p><a href=\"https:\/\/doi.org\/10.1021\/acs.nanolett.3c04243\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1021\/acs.nanolett.3c04243<\/a><\/p>\n<h3>Development Phase<\/h3>\n<p>Current stage:<br \/>\nWe have obtained a POC for a deuterated system with prototype equipment. Implementation cases and mechanism verification ongoing.<\/p>\n<p>Next stage:<br \/>\n1-i) Evaluation of the versatility of deuterated compounds, evaluation of material development.<br \/>\n1-ii) Commercialization of the device through the development of mass production equipment.<br \/>\n2 Catalyst development, optimization and application development for further reaction efficiency.<\/p>\n<p>All of the above can be done in collaboration\/joint development with research laboratories. We are looking for partner companies interested in evaluating target compounds using this technology\/process, joint research\/development collaboration and technical guidance. We would be happy to start with a detailed description and discussion of the technology.<\/p>\n<p>&nbsp;<\/p>\n<p>Project ID:ON-04951b<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Collaboration proposal for flow synthesis equipment development<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"categories":[1],"tags":[],"categories_of_inventions":[],"disease_categories___indication":[],"asset_type":[],"development_phase":[],"medicine":[147,121],"other_than_medicine":[146,141],"material":[],"engineering":[157,156],"software_it":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/bionauts.jp\/index.php?rest_route=\/wp\/v2\/posts\/4651"}],"collection":[{"href":"https:\/\/bionauts.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bionauts.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4651"}],"version-history":[{"count":2,"href":"https:\/\/bionauts.jp\/index.php?rest_route=\/wp\/v2\/posts\/4651\/revisions"}],"predecessor-version":[{"id":4654,"href":"https:\/\/bionauts.jp\/index.php?rest_route=\/wp\/v2\/posts\/4651\/revisions\/4654"}],"wp:attachment":[{"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4651"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4651"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4651"},{"taxonomy":"categories_of_inventions","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories_of_inventions&post=4651"},{"taxonomy":"disease_categories___indication","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fdisease_categories___indication&post=4651"},{"taxonomy":"asset_type","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fasset_type&post=4651"},{"taxonomy":"development_phase","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fdevelopment_phase&post=4651"},{"taxonomy":"medicine","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedicine&post=4651"},{"taxonomy":"other_than_medicine","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fother_than_medicine&post=4651"},{"taxonomy":"material","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmaterial&post=4651"},{"taxonomy":"engineering","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fengineering&post=4651"},{"taxonomy":"software_it","embeddable":true,"href":"https:\/\/bionauts.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fsoftware_it&post=4651"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}