New therapeutic targets and therapeutic agents for trauma-induced heterotopic ossification in FOP patients.
An approach to enhance mechanical stress responsiveness via activation of Piezo1 shows promise in improving bone mass and strength in patients with glucocorticoid-induced osteoporosis (GIOP).
Two types of seed small molecule compounds (CRY1-A, CRY2-A) that selectively activate the circadian clock regulators CRY1 and CRY2, respectively.
Orally available micelle-type branched-chain amino acid prodrug
Improvement of cilial dysfunction by FGFR inhibitor through ICK/MAK pathway activation.
Identification of prostaglandin receptors involved in the pathogenesis of endometriosis. [Collaborative Research Proposal]
Substance derived from seaweed “Padina extract” 2-hydroxypentanoic acid
Runx2 expression was specifically induced in osteoblasts. Bone volume was increased through the enhanced bone formation in mice.
Original method and hepatocyte reproduced hepatobiliary function
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